High-resolution three-dimensional extracellular recording of neuronal activity with microfabricated electrode arrays.

Abstract

Microelectrode array recordings of neuronal activity present significant opportunities for studying the brain with single-cell and spike-time precision. However, challenges in device manufacturing constrain dense multisite recordings to two spatial dimensions, whereas access to the three-dimensional (3D) structure of many brain regions appears to remain a… (More)
DOI: 10.1152/jn.90992.2008

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