High resolution spectroscopic imaging of GABA at 3 Tesla.

  title={High resolution spectroscopic imaging of GABA at 3 Tesla.},
  author={He Zhu and Richard A. E. Edden and Ronald Ouwerkerk and Peter B. Barker},
  journal={Magnetic resonance in medicine},
  volume={65 3},
A spin echo-based MRSI sequence was developed to acquire edited spectra of γ-aminobutyric acid in an entire slice. Water and lipid signals were suppressed by a dual-band presaturation sequence, which included integrated outer volume suppression pulses for additional lipid suppression. Experiments in three normal volunteers were performed at 3 T using a 32-channel head coil. High signal-to-noise ratio spectra and metabolic images of γ-aminobutyric acid were acquired from nominal 4.5 cm3 voxels… CONTINUE READING
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