High-resolution pulmonary ventilation and perfusion PET/CT allows for functionally adapted intensity modulated radiotherapy in lung cancer.

@article{Siva2015HighresolutionPV,
  title={High-resolution pulmonary ventilation and perfusion PET/CT allows for functionally adapted intensity modulated radiotherapy in lung cancer.},
  author={Shankar Siva and Roshini Thomas and J. Ken Callahan and Nicholas Hardcastle and Daniel Pham and Tomas Kron and Rodney J Hicks and Michael P Macmanus and David Ball and Michael S Hofman},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={2015},
  volume={115 2},
  pages={157-62}
}
BACKGROUND AND PURPOSE To assess the utility of functional lung avoidance using IMRT informed by four-dimensional (4D) ventilation/perfusion (V/Q) PET/CT. MATERIALS AND METHODS In a prospective clinical trial, patients with non-small cell lung cancer (NSCLC) underwent 4D-V/Q PET/CT scanning before 60Gy of definitive chemoradiation. Both "highly perfused" (HPLung) and "highly ventilated" (HVLung) lung volumes were delineated using a 70th centile SUV threshold, and a "ventilated lung volume… CONTINUE READING
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Feasibility of IMRT planning to reduce dose to functional lung using respiratory gated (4D) gallium-68 Perfusion PET/ CT

  • S Siva, T Devereux, N Hardcastle
  • Int J Radiat Oncol Biol Phys 2014;90:S618–9
  • 2014
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