High-resolution proteomic mapping in the vertebrate central nervous system: close proximity of connexin35 to NMDA glutamate receptor clusters and co-localization of connexin36 with immunoreactivity for zonula occludens protein-1 (ZO-1).

@article{Rash2004HighresolutionPM,
  title={High-resolution proteomic mapping in the vertebrate central nervous system: close proximity of connexin35 to NMDA glutamate receptor clusters and co-localization of connexin36 with immunoreactivity for zonula occludens protein-1 (ZO-1).},
  author={John E Rash and Alex Pereda and Naomi Kamasawa and C Sue Furman and Thomas Yasumura and Kimberly G. V. Davidson and F. Edward Dudek and Carl O. Olson and X-b Li and J. I. Nagy},
  journal={Journal of neurocytology},
  year={2004},
  volume={33 1},
  pages={131-51}
}
Combined confocal microscopy and freeze-fracture replica immunogold labeling (FRIL) were used to examine the connexin identity at electrical synapses in goldfish brain and rat retina, and to test for "co-localization" vs. "close proximity" of connexins to other functionally interacting proteins in synapses of goldfish and mouse brain and rat retina. In goldfish brain, confocal microscopy revealed immunofluorescence for connexin35 (Cx35) and NMDA-R1 (NR1) glutamate receptor protein in Mauthner… CONTINUE READING

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