High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources

@inproceedings{Haraszti2016HighresolutionPA,
  title={High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources},
  author={Reka Agnes Haraszti and Marie-C{\'e}cile Didiot and Ellen Sapp and John D. Leszyk and Scott A Shaffer and Hannah E. Rockwell and Fei Gao and Niven R. Narain and Marian Difiglia and Michael A. Kiebish and Neil Aronin and Anastasia Khvorova},
  booktitle={Journal of extracellular vesicles},
  year={2016}
}
Extracellular vesicles (EVs), including exosomes and microvesicles (MVs), are explored for use in diagnostics, therapeutics and drug delivery. However, little is known about the relationship of protein and lipid composition of EVs and their source cells. Here, we report high-resolution lipidomic and proteomic analyses of exosomes and MVs derived by differential ultracentrifugation from 3 different cell types: U87 glioblastoma cells, Huh7 hepatocellular carcinoma cells and human bone marrow… CONTINUE READING
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