High-resolution melting analysis of MED12 mutations in uterine leiomyomas in Chinese patients.

@article{Wang2015HighresolutionMA,
  title={High-resolution melting analysis of MED12 mutations in uterine leiomyomas in Chinese patients.},
  author={Hua Wang and Jun Ye and Hua Qian and Ruifang Zhou and Jun Jiang and Lihua Ye},
  journal={Genetic testing and molecular biomarkers},
  year={2015},
  volume={19 3},
  pages={162-6}
}
OBJECTIVES Somatic mutations in mediator complex subunit 12 (MED12) have emerged as a critical genetic change in the development of uterine leiomyomas. Studies, however, have focused largely on cohorts consisting of Caucasian patients. In this study, uterine leiomyomas from Chinese patients were examined for MED12 mutations. In addition, polymerase chain… CONTINUE READING