High resolution mapping of Twist to DNA in Drosophila embryos: Efficient functional analysis and evolutionary conservation.

@article{Ozdemir2011HighRM,
  title={High resolution mapping of Twist to DNA in Drosophila embryos: Efficient functional analysis and evolutionary conservation.},
  author={Anil Ozdemir and Katherine I. Fisher-Aylor and Shirley Pepke and Manoj Samanta and Leslie A Dunipace and Kenneth McCue and Lucy Zeng and Nobuo Ogawa and Barbara J. Wold and Angelike Stathopoulos},
  journal={Genome research},
  year={2011},
  volume={21 4},
  pages={566-77}
}
Cis-regulatory modules (CRMs) function by binding sequence specific transcription factors, but the relationship between in vivo physical binding and the regulatory capacity of factor-bound DNA elements remains uncertain. We investigate this relationship for the well-studied Twist factor in Drosophila melanogaster embryos by analyzing genome-wide factor occupancy and testing the functional significance of Twist occupied regions and motifs within regions. Twist ChIP-seq data efficiently… CONTINUE READING
Highly Cited
This paper has 39 citations. REVIEW CITATIONS