High resolution localization of angiotensin II receptors in rat renal medulla.

@article{Zhuo1992HighRL,
  title={High resolution localization of angiotensin II receptors in rat renal medulla.},
  author={Jia Long Zhuo and Daine Alcorn and Andrew M Allen and Frederick A O Mendelsohn},
  journal={Kidney international},
  year={1992},
  volume={42 6},
  pages={1372-80}
}
The cellular localization of angiotensin II (Ang II) receptors in the inner stripe of the outer medulla of the rat kidney was investigated by using high resolution light and electron microscopic autoradiography. Fresh tissue blocks from the inner stripe of the outer medulla were incubated with 125I-[Sar1, Ile8] Ang II and prepared for microscopic autoradiography. At the light microscopic level, 125I-[Sar1, Ile8] Ang II was found to penetrate into the tissue and to bind specifically to sites… CONTINUE READING