High-resolution genomic profiling to predict 10-year overall survival in node-negative breast cancer.

@article{Mllerstrm2010HighresolutionGP,
  title={High-resolution genomic profiling to predict 10-year overall survival in node-negative breast cancer.},
  author={Elin M{\"o}llerstr{\"o}m and Ulla Delle and Anna Danielsson and Toshima Z. Parris and Bj{\"o}rn Olsson and Per O Karlsson and Khalil Helou},
  journal={Cancer genetics and cytogenetics},
  year={2010},
  volume={198 2},
  pages={79-89}
}
Women with clinically node-negative breast cancer have a better prognosis than do those with axillary lymph node metastasis. Nonetheless, approximately 20% of node-negative patients die within 15 years of diagnosis, and thus additional prognostic markers are greatly needed. To identify specific copy number alterations (CNAs) that differed in frequency between 10-year survivors and deceased patients with node-negative breast cancer, array comparative genomic hybridization (aCGH) was applied to… CONTINUE READING

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