High-resolution genomic profiling of pediatric lymphoblastic lymphomas reveals subtle differences with pediatric acute lymphoblastic leukemias in the B-lineage.

@article{Schraders2009HighresolutionGP,
  title={High-resolution genomic profiling of pediatric lymphoblastic lymphomas reveals subtle differences with pediatric acute lymphoblastic leukemias in the B-lineage.},
  author={Margit Schraders and Simon V. van Reijmersdal and Eveline J Kamping and Johan H. J. M. van Krieken and Ad Geurts van Kessel and Patricia J. T. A. Groenen and Peter M. Hoogerbrugge and Roland P Kuiper},
  journal={Cancer genetics and cytogenetics},
  year={2009},
  volume={191 1},
  pages={27-33}
}
Lymphoblastic lymphoma (LBL) is one of the most frequent occurring pediatric non-Hodgkin lymphomas. In the WHO classification scheme, pediatric LBL is considered to be the same disease entity as pediatric acute lymphoblastic leukemia (ALL). However, it is unclear whether the genetic basis of pediatric LBL development is similar to that of pediatric ALL. We performed genome-wide analyses of copy number aberrations in 12 T-LBL and 7 precursor B-cell LBL pediatric cases using high-resolution SNP… CONTINUE READING

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