High-resolution fluorescence microscopy to study transendothelial migration.

Immune system functions rely heavily on the ability of immune cells (i.e., blood leukocyte) to traffic throughout the body as they conduct immune surveillance and respond to pathogens. A monolayer of vascular endothelial cells (i.e., the "endothelium") provides a critical, selectively permeable barrier between two principal compartments of the body: the… CONTINUE READING