High-resolution fluorescence in situ hybridization of human Y-linked genes on released chromatin

@article{Glaser1997HighresolutionFI,
  title={High-resolution fluorescence in situ hybridization of human Y-linked genes on released chromatin},
  author={Birgitta Gla¨ser and Thomas Hierl and Kay Taylor and Katrin Schiebel and Sylvia Zeitler and Katia Papadopoullos and Gudrun A Rappold and Werner Schempp},
  journal={Chromosome Research},
  year={1997},
  volume={5},
  pages={23-30}
}
Genes within the differential region of the human Y chromosome do not recombine, and therefore the determination of their location depends on physical mapping. Yeast artificial chromosome (YAC) contigs spanning the euchromatic region of the human Y have become a powerful tool for the generation of an overlapping clone map. With this approach,however, complete physical mapping is difficult in Y euchromatic regions that are rich in repetitive sequences. We have, therefore, made use of the… CONTINUE READING
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Human HY–A male specific histocompatibility antigen derived from the SMCY protein

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  • Science
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Highly Influential
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