High-resolution analysis of Mammalian DNA replication units.

Abstract

Genomic DNA of a eukaryotic cell is replicated once during the S-phase of the cell cycle to precisely maintain the complete genetic information. In the course of S-phase, semiconservative DNA synthesis is sequentially initiated and performed at thousands of discrete patches of the DNA helix termed replicons. At any given moment of S-phase, multiple… (More)
DOI: 10.1007/978-1-4939-2596-4_3

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