High reproducibility of tumor hypoxia evaluated by 18F-fluoromisonidazole PET for head and neck cancer.

@article{Okamoto2013HighRO,
  title={High reproducibility of tumor hypoxia evaluated by 18F-fluoromisonidazole PET for head and neck cancer.},
  author={Shozo Okamoto and Tohru Shiga and Koichi Yasuda and Yoichi M Ito and Keiichi Magota and Katsuhiko Kasai and Yuji Kuge and Hiroki Shirato and N. Tamaki},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2013},
  volume={54 2},
  pages={201-7}
}
UNLABELLED Tumor hypoxia is well known to be radiation resistant. (18)F-fluoromisonidazole ((18)F-FMISO) PET has been used for noninvasive evaluation of hypoxia. Quantitative evaluation of (18)F-FMISO uptake is thus expected to play an important role in the planning of dose escalation radiotherapy. However, the reproducibility of (18)F-FMISO uptake has remained unclarified. We therefore investigated the reproducibility of tumor hypoxia by using quantitative analysis of (18)F-FMISO uptake… CONTINUE READING
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