High rates of survival, immune reconstitution, and virologic suppression on second-line antiretroviral therapy in South Africa.

@article{Fox2010HighRO,
  title={High rates of survival, immune reconstitution, and virologic suppression on second-line antiretroviral therapy in South Africa.},
  author={Matthew P Fox and Prudence D Ive and Lawrence Stephen Long and Mhairi Maskew and Ian M. Sanne},
  journal={Journal of acquired immune deficiency syndromes},
  year={2010},
  volume={53 4},
  pages={500-6}
}
To determine rates of survival, viral suppression, and immunologic change after 1 year on second-line antiretroviral therapy, we conducted a cohort study among 328 patients initiated on zidovudine, didanosine, and lopinavir/ritonavir. All patients who switched to standard second-line therapy at a large urban public-sector clinic in Johannesburg, South Africa, were included. A year after initiating second-line therapy 243/313 [78%; 95% confidence interval (CI) 73%-82%], subjects were alive and… CONTINUE READING

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