High rates of forward transmission events after acute/early HIV-1 infection.

  title={High rates of forward transmission events after acute/early HIV-1 infection.},
  author={Bluma G Brenner and M. Roger and Jean-pierre Routy and Daniela D Moisi and Michel Ntemgwa and Claudine Matte and J G Baril and R{\'e}jean Thomas and Danielle Rouleau and Julie Bruneau and Roger Leblanc and Mario Legault and C{\'e}cile Tremblay and Hugues Charest and Mark A. Wainberg},
  journal={The Journal of infectious diseases},
  volume={195 7},
BACKGROUND A population-based phylogenetic approach was used to characterize human immunodeficiency virus (HIV)-transmission dynamics in Quebec. METHODS HIV-1 pol sequences included primary HIV infections (PHIs; <6 months after seroconversion) from the Quebec PHI cohort (1998-2005; n=215) and the provincial genotyping program (2001-2005; n=481). Phylogenetic analysis determined sequence interrelationships among unique PHIs (n=593) and infections from untreated (n=135) and treated (n=660… CONTINUE READING
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