High rate of viral evolution associated with the emergence of carnivore parvovirus.

  title={High rate of viral evolution associated with the emergence of carnivore parvovirus.},
  author={Laura A. Shackelton and Colin R Parrish and Uwe Truyen and Edward C. Holmes},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={102 2},
Canine parvovirus (CPV) is an emerging DNA virus that was first observed to cause disease in canines in 1978 and has since become a ubiquitous pathogen worldwide. CPV emerged from feline panleukopenia parvovirus (FPLV) or a closely related virus, differing at several key amino acid residues. Here we characterize the evolutionary processes underlying the emergence of CPV. Although FPLV has remained an endemic infection in its host populations, we show that, since the 1970s, the newly emerged CPV… CONTINUE READING
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