High rate of positive anti-tissue transglutaminase antibodies in chronic liver disease. Role of liver decompensation and of the antigen source.

@article{Vecchi2003HighRO,
  title={High rate of positive anti-tissue transglutaminase antibodies in chronic liver disease. Role of liver decompensation and of the antigen source.},
  author={Maurizio Vecchi and Christian Folli and Maria Francesca Donato and Sara Formenti and Eliana Arosio and Roberto de Franchis},
  journal={Scandinavian journal of gastroenterology},
  year={2003},
  volume={38 1},
  pages={50-4}
}
BACKGROUND Since the recognition of tissue transglutaminase (tTG) as the target antigen of anti-endomysium antibodies, several ELISA assays using either guinea pig or human recombinant tTG have been developed. The aim of the study was to compare the behaviour of anti-tTG and anti-endomysium antibodies assays in coeliacs and in patients with chronic liver disease. METHODS 34 patients (24 women, 34.9 +/- 12.5 years) with coeliac disease and 41 with chronic liver disease (14 women, 57 +/- 11.2… CONTINUE READING
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