High rate of mixoploidy among human blastocysts cultured in vitro.

  title={High rate of mixoploidy among human blastocysts cultured in vitro.},
  author={Magdalena Bielanska and Seang Lin Tan and Asangla Ao},
  journal={Fertility and sterility},
  volume={78 6},
OBJECTIVE To determine the incidence and type of mixoploidy in human blastocysts produced in vitro. DESIGN A laboratory study of spare blastocysts from an IVF program. SETTING University hospital laboratory. PATIENT(S) Thirty-nine couples undergoing IVF or intracytoplasmic sperm injection. INTERVENTION(S) A total of 103 blastocysts were classified as good- or poor-quality blastocysts based on morphology. A total of 6,927 interphase nuclei, 5,015 from 59 good-quality and 1,912 from 44… CONTINUE READING


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