High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development

@article{Daccord2017HighqualityDN,
  title={High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development},
  author={N. Daccord and Jean-Marc Celton and G. Linsmith and Claude Becker and N. Choisne and E. Schijlen and H. van de Geest and L. Bianco and D. Micheletti and R. Velasco and E. A. Di Pierro and J. Gouzy and D. Rees and P. Gu{\'e}rif and H. Muranty and C. Durel and F. Laurens and Y. Lespinasse and S. Gaillard and S. Aubourg and H. Quesneville and D. Weigel and E. van de Weg and M. Troggio and E. Bucher},
  journal={Nature Genetics},
  year={2017},
  volume={49},
  pages={1099-1106}
}
Using the latest sequencing and optical mapping technologies, we have produced a high-quality de novo assembly of the apple (Malus domestica Borkh.) genome. Repeat sequences, which represented over half of the assembly, provided an unprecedented opportunity to investigate the uncharacterized regions of a tree genome; we identified a new hyper-repetitive retrotransposon sequence that was over-represented in heterochromatic regions and estimated that a major burst of different transposable… Expand
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