High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development

@article{Daccord2017HighqualityDN,
  title={High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development},
  author={Nicolas Daccord and Jean Marc Celton and Gareth Linsmith and Claude Becker and Nathalie Choisne and Elio Schijlen and Henri van de Geest and Luca Di Bianco and Diego Micheletti and Riccardo Velasco and Erica Adele Di Pierro and J{\'e}r{\^o}me Gouzy and David Jasper Gilbert Rees and Philippe Gu{\'e}rif and H{\'e}l{\`e}ne Muranty and C. E. Durel and François Laurens and Yves Lespinasse and Sylvain Gaillard and S{\'e}bastien Aubourg and Hadi Quesneville and Detlef Weigel and Eric van de Weg and Michela Troggio and Etienne Bucher},
  journal={Nature Genetics},
  year={2017},
  volume={49},
  pages={1099-1106}
}
Using the latest sequencing and optical mapping technologies, we have produced a high-quality de novo assembly of the apple (Malus domestica Borkh.) genome. Repeat sequences, which represented over half of the assembly, provided an unprecedented opportunity to investigate the uncharacterized regions of a tree genome; we identified a new hyper-repetitive retrotransposon sequence that was over-represented in heterochromatic regions and estimated that a major burst of different transposable… 
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