High-purity enrichment of functional cardiovascular cells from human iPS cells.

@article{Lin2012HighpurityEO,
  title={High-purity enrichment of functional cardiovascular cells from human iPS cells.},
  author={Bo Lin and Jong Kim and Yanxin Li and Haiying Pan and Xonia Carvajal-Vergara and Guy Salama and Tao Cheng and Yuanzheng Li and Cecilia W. Lo and Lei Yang},
  journal={Cardiovascular research},
  year={2012},
  volume={95 3},
  pages={327-35}
}
AIMS A variety of human inherited heart diseases affect the normal functions of cardiomyocytes (CMs), endothelial cells (ECs), or smooth muscle cells (SMCs). To study human heart disease and generate cardiac cells for basic and translational research, an efficient strategy is needed for production of cardiac lineages from human stem cells. In the present study, a highly reproducible method was developed that can simultaneously enrich a large number of CMs and cardiac SMCs and ECs from human… CONTINUE READING
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