High proton relaxivity for gadolinium oxide nanoparticles

  title={High proton relaxivity for gadolinium oxide nanoparticles},
  author={Maria Engström and Anna Klasson and Henrik Pedersen and Cecilia Vahlberg and Per-Olov Käll and Kajsa Uvdal},
  journal={Magnetic Resonance Materials in Physics, Biology and Medicine},
AbstractObjective: Nanosized materials of gadolinium oxide can provide high-contrast enhancement in magnetic resonance imaging (MRI). The objective of the present study was to investigate proton relaxation enhancement by ultrasmall (5 to 10 nm) Gd2O3 nanocrystals. Materials and methods: Gd2O3 nanocrystals were synthesized by a colloidal method and capped with diethylene glycol (DEG). The oxidation state of Gd2O3 was confirmed by X-ray photoelectron spectroscopy. Proton relaxation times were… 
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Paramagnetic Metal Complexes as Water Proton Relaxation Agents for NMR Imaging : Theory and Design
  • E.
  • Medicine, Chemistry
  • 2001
Peter Lauffer's research interests are in the areas of bwinorganic chemistry and NMR, focusing in particular on the interactions between metal complexes and proteins and the development and characterization of metal complexes as diagnostic agents for NMR imaging.
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Temperature dependence of proton relaxation times in vitro.