High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health.

@article{Russell2011HighproteinRW,
  title={High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health.},
  author={W. Randall Russell and Silvia Wilson Gratz and S. H. Duncan and Grietje Holtrop and Jennifer Ince and Lorraine Scobbie and Garry A. Duncan and A. M. Johnstone and Gerald E. Lobley and Robert J. Wallace and Garry G. Duthie and Harry James Flint},
  journal={The American journal of clinical nutrition},
  year={2011},
  volume={93 5},
  pages={1062-72}
}
BACKGROUND Diets that are high in protein but reduced in carbohydrate contents provide a common approach for achieving weight loss in obese humans. However, the effect of such diets on microbiota-derived metabolites that influence colonic health has not been established. OBJECTIVE We designed this study to assess the effect of diets with reduced carbohydrate and increased protein contents on metabolites considered to influence long-term colonic health, in particular the risk of colorectal… CONTINUE READING
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