High production of 1,3-propanediol from glycerol by Clostridium butyricum VPI 3266 in a simply controlled fed-batch system

  title={High production of 1,3-propanediol from glycerol by Clostridium butyricum VPI 3266 in a simply controlled fed-batch system},
  author={Sylvie Saint-Amans and Patrice Perlot and Gerard Goma and Philippe Soucaille},
  journal={Biotechnology Letters},
SummaryA simple fed-batch system which controls substrate feeding by measuring the CO2 produced during the fermentation, was developped. This Fed-batch approach allowed high production of 1,3-propanediol from glycerol by Clostridium butyricum by avoiding substrate inhibition phenomena. 65 g/l of 1,3-propanediol was produced with a productivity of 1.21 g/l.h and a yield of 0.56. The concentration of 1,3-propanediol obtained and the productivity were significantly higher than those reached in… Expand

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Production of 1,3-Propanediol from Glycerol by Clostridium acetobutylicum and Other Clostridium Species
  • C. Forsberg
  • Medicine, Chemistry
  • Applied and environmental microbiology
  • 1987
Glycerol was fermented with the production of 1,3-propanediol as the major fermentation product by four strains of Clostridium acetobutylicum and three of C. butyricum, and 1, 3-Propanediol was identified by its retention times in gas chromatography and high-pressure liquid chromatographyand by its mass spectrum. Expand
Glycerol conversion to 1,3-propanediol by newly isolated clostridia
The observations point to a substantial transfer of reducing potential from ferredoxin to NAD, which finally results in increased 1,3-propanediol production. Expand
Fermentative production of 1,3-propanediol from glycerol by Clostridium butyricum up to a scale of 2m3
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Anaerobic Reduction of Glycerol to Propanediol-1.3 by Lactobacillus brevis and Lactobacillus buchneri
Three strains of L. brevis and one strain of Lactobacillus buchneri grew very poorly on glucose; while glucose was fermented to acetate or ethanol, lactate and CO 2 , glycerol was dehydrated to 3-hydroxypropanal and subsequently reduced to propanediol-1.3. Expand
The fermentation of glycerol byClostridium butyricum LMG 1212t2 and 1213t1 andC. pasteurianum LMG 3285
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Regulation of carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH on mixtures of glucose and glycerol
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Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases
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