High production of 1,3-propanediol from glycerol by Clostridium butyricum VPI 3266 in a simply controlled fed-batch system

@article{SaintAmans2004HighPO,
  title={High production of 1,3-propanediol from glycerol by Clostridium butyricum VPI 3266 in a simply controlled fed-batch system},
  author={Sylvie Saint-Amans and Patrice Perlot and Gerard Goma and Philippe Soucaille},
  journal={Biotechnology Letters},
  year={2004},
  volume={16},
  pages={831-836}
}
SummaryA simple fed-batch system which controls substrate feeding by measuring the CO2 produced during the fermentation, was developped. This Fed-batch approach allowed high production of 1,3-propanediol from glycerol by Clostridium butyricum by avoiding substrate inhibition phenomena. 65 g/l of 1,3-propanediol was produced with a productivity of 1.21 g/l.h and a yield of 0.56. The concentration of 1,3-propanediol obtained and the productivity were significantly higher than those reached in… Expand

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