High prevalence of plasma lipid abnormalities in human and canine Duchenne and Becker muscular dystrophies depicts a new type of primary genetic dyslipidemia.

@article{White2020HighPO,
  title={High prevalence of plasma lipid abnormalities in human and canine Duchenne and Becker muscular dystrophies depicts a new type of primary genetic dyslipidemia.},
  author={Zoe White and Chady H Hakim and Marine Theret and N. Nora Yang and Fabio M. V. Rossi and D Cox and Gordon A. Francis and Volker Straub and Kathryn Selby and Constadina Panagiotopoulos and Dongsheng Duan and Pascal Bernatchez},
  journal={Journal of clinical lipidology},
  year={2020}
}
BACKGROUND Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are allelic X-linked recessive muscle diseases caused by mutations in the DMD gene, with DMD being the more severe form. We have recently shown that increased plasma low-density lipoprotein-associated cholesterol causes severe muscle wasting in the mdx mouse, a mild DMD model, which suggested that plasma lipids may play a critical role in DMD. We have also observed that loss of dystrophin in mice causes unexpected… 
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