High prevalence of mutators among Enterobacter cloacae nosocomial isolates and their association with antimicrobial resistance and repetitive detection.

Abstract

We determined the mutation frequencies of 59 nosocomial isolates of Enterobacter cloacae, and investigated their association with antimicrobial susceptibility, genotype, and history of exposure to antimicrobials. The frequencies of mutations leading to rifampicin resistance ranged from 5.8 × 10(-9) to 8.0 × 10(-6) (median, 5.0 × 10(-8)). Seven of the 59 (12… (More)
DOI: 10.1111/j.1469-0691.2009.03145.x

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@article{Matsushima2010HighPO, title={High prevalence of mutators among Enterobacter cloacae nosocomial isolates and their association with antimicrobial resistance and repetitive detection.}, author={Ayako Matsushima and Satoshi Takakura and Naoka Fujihara and Toru Saito and Isao Ito and Yoshitsugu Iinuma and Satoshi Ichiyama}, journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases}, year={2010}, volume={16 9}, pages={1488-93} }