High prevalence of intermittent acute porphyria in a psychiatric patient population.

@article{Tishler1985HighPO,
  title={High prevalence of intermittent acute porphyria in a psychiatric patient population.},
  author={Peter V. Tishler and B. Woodward and John W. O'connor and Diana Holbrook and Larry J. Seidman and Mark Hallett and D. J. Knighton},
  journal={The American journal of psychiatry},
  year={1985},
  volume={142 12},
  pages={
          1430-6
        }
}
The authors screened 3,867 psychiatric inpatients for intermittent acute porphyria by use of a spot test to detect diminished activity of the erythrocyte enzyme porphobilinogen (PBG) deaminase. Eighteen individuals so identified also had persistently diminished quantitative activity of PBG deaminase. Eight of these appeared to have intermittent acute porphyria by the added criteria of increased urinary delta-aminolevulinic acid or PBG or a family history of intermittent acute porphyria. The… CONTINUE READING

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