High prevalence of human papillomavirus in squamous cell carcinoma and matched normal esophageal mucosa: assessment by polymerase chain reaction.

@article{Fidalgo1995HighPO,
  title={High prevalence of human papillomavirus in squamous cell carcinoma and matched normal esophageal mucosa: assessment by polymerase chain reaction.},
  author={Paulo O Fidalgo and Marilia L. Cravo and Paolo Chaves and Carlos Nobre Leit{\~a}o and Filipe Mira},
  journal={Cancer},
  year={1995},
  volume={76 9},
  pages={1522-8}
}
BACKGROUND Studies using DNA technology have reported the presence of human papillomavirus (HPV) DNA in esophageal carcinomas, suggesting that it could play a role in the pathogenesis of this tumor. In the present study, in addition to DNA from neoplasms, normal mucosa was screened for viral DNA, assuming that this would increase HPV detection substantially… CONTINUE READING