High prevalence of cobalamin deficiency in elderly outpatients.

  title={High prevalence of cobalamin deficiency in elderly outpatients.},
  author={L C Pennypacker and Robert H. Allen and John P. Kelly and Lacey Matthews and Jim Grigsby and Kaye Kaye and John Lindenbaum and Sally P. Stabler},
  journal={Journal of the American Geriatrics Society},
  volume={40 12},
OBJECTIVE To measure the prevalence of cobalamin (vitamin B12) deficiency in geriatric outpatients as documented by both low serum cobalamin levels and elevations of serum methylmalonic acid and homocysteine and to determine the response to cobalamin treatment. DESIGN Prospective study screening elderly subjects for cobalamin deficiency using radiodilution cobalamin assays as well as stable isotope dilution gas chromatography-mass spectrometry methylmalonic acid and homocysteine assays. In… CONTINUE READING
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