High prevalence of Plamodium malariae infections in a Brazilian Amazon endemic area (Apiacás-Mato Grosso State) as detected by polymerase chain reaction.

@article{Scopel2004HighPO,
  title={High prevalence of Plamodium malariae infections in a Brazilian Amazon endemic area (Apiac{\'a}s-Mato Grosso State) as detected by polymerase chain reaction.},
  author={K{\'e}zia K.G. Scopel and Cor Jesus Fernandes Fontes and {\'A}. Nunes and Maria de F{\'a}tima Horta and {\'E}rika Martins Braga},
  journal={Acta tropica},
  year={2004},
  volume={90 1},
  pages={61-4}
}
Plasmodium malariae is commonly confounded with Plasmodium vivax at the microscopic examination of thick blood smear. In the present study, we used a nested PCR assay to amplify a species-specific sequence of the 18S SSU rRNA gene of Plasmodium in blood samples of 497 individuals living in an endemic region of the Brazilian Amazon basin. We have found that, while the microscopic examination of thick blood smears showed a P. malariae prevalence of 1.2% (6 out of 497), the nested PCR revealed 11… CONTINUE READING

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