High prevalence of MMTV-like env gene sequences in gestational breast cancer.

@article{Wang2003HighPO,
  title={High prevalence of MMTV-like env gene sequences in gestational breast cancer.},
  author={Ying K. Wang and Stella M. Melana and Bilal Baker and Ira J. Bleiweiss and Mariana Fernandez-Cobo and John Mandeli and James F. Holland and Beatriz G. T. Pogo},
  journal={Medical oncology},
  year={2003},
  volume={20 3},
  pages={233-6}
}
Gestational breast cancer (BC) is generally associated with rapid growth and increased mortality. Because the presence of MMTV-like sequences in BC has been associated with laminin receptor expression, a marker of poor prognosis, gestational BCs were analyzed for MMTV env gene-like sequences to explore whether MMTV-like sequences were also associated with its adverse outcome. Whereas 30-38% of sporadic BC have the sequences, in gestational BC the prevalence is 62%. We suggest that hormonal… CONTINUE READING

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