High-pressure liquid chromatographic assay of theophylline, ephedrine hydrochloride, and phenobarbital tablets.

@article{Chen1981HighpressureLC,
  title={High-pressure liquid chromatographic assay of theophylline, ephedrine hydrochloride, and phenobarbital tablets.},
  author={T. M. Chen and Lester Chafetz},
  journal={Journal of pharmaceutical sciences},
  year={1981},
  volume={70 7},
  pages={
          804-6
        }
}
An innovation high-pressure liquid chromatographic method is described in which theophylline, ephedrine hydrochloride (measured as benzaldehyde), and phenobarbital are determined simultaneously with butabarbital as the internal standard. Chromatographic conditions were selected to afford a pH sufficient for rapid oxidation of ephedrine and relatively high UV absorbance for the barbiturates and a detection wavelength near the maximum for benzaldehyde and the barbiturates and the minimum for… 
5 Citations
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Two methods are described for the simultaneous determination of theophylline and guaiphenesin in combined pharmaceutical dosage forms based on third-derivative ultraviolet spectrophotometry and high-performance liquid chromatography.
The Analysis of Theophylline — Containing Pharmaceuticals by Room Temperature Phosphorescence
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Abstract A new stopped-flow kinetic spectrophotometric method for determination of reactants based on monitoring the signal change of intermediates for successive reactions is proposed. Using this

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