High-pressure liquid chromatographic assay of theophylline, ephedrine hydrochloride, and phenobarbital tablets.
@article{Chen1981HighpressureLC,
title={High-pressure liquid chromatographic assay of theophylline, ephedrine hydrochloride, and phenobarbital tablets.},
author={T. M. Chen and Lester Chafetz},
journal={Journal of pharmaceutical sciences},
year={1981},
volume={70 7},
pages={
804-6
}
}An innovation high-pressure liquid chromatographic method is described in which theophylline, ephedrine hydrochloride (measured as benzaldehyde), and phenobarbital are determined simultaneously with butabarbital as the internal standard. Chromatographic conditions were selected to afford a pH sufficient for rapid oxidation of ephedrine and relatively high UV absorbance for the barbiturates and a detection wavelength near the maximum for benzaldehyde and the barbiturates and the minimum for…
5 Citations
A simultaneous assay of theophylline, ephedrine hydrochloride and phenobarbital in suspensions and tablets formulations by high performance liquid chromatography
- Chemistry
- 1986
Abstract A simple reversed phase high-performance liquid chromatographic (HPLC) procedure is described for simultaneous determination of Theophylline, Ephedrine Hydrochloride and Phenobarbital in…
Simultaneous determination of theophylline and guaiphenesin by third-derivative ultraviolet spectrophotometry and high-performance liquid chromatography.
- ChemistryThe Analyst
- 1992
Two methods are described for the simultaneous determination of theophylline and guaiphenesin in combined pharmaceutical dosage forms based on third-derivative ultraviolet spectrophotometry and high-performance liquid chromatography.
The Analysis of Theophylline — Containing Pharmaceuticals by Room Temperature Phosphorescence
- Chemistry
- 1982
Abstract A simple and specific technique is used in analyzing pharmaceutical preparations (capsules, elixirs, syrups, and tablets) for theophylline and related compounds. The procedure consists of…
Determination of Theophylline Based on Monitoring the Oxidation Intermediate by a Stopped-Flow Kinetic Spectrophotometric Method
- Chemistry
- 1998
Abstract A new stopped-flow kinetic spectrophotometric method for determination of reactants based on monitoring the signal change of intermediates for successive reactions is proposed. Using this…
References
SHOWING 1-4 OF 4 REFERENCES
Determination of ephedrine, phenobarbital, and theophylline in tablets by gas chromatography.
- Chemistry, BiologyJournal of pharmaceutical sciences
- 1967
A gas chromatographic procedure is described for the rapid, specific, and precise determination of ephedrine, phenobarbital, and theophylline in tablets. Ephedrine is converted to benzaldehyde by…
Quantitative GLC analysis of theophylline, ephedrine hydrochloride, and phenobarbital suspension.
- ChemistryJournal of pharmaceutical sciences
- 1973
A rapid GLC method was developed for the quantitative determination of theophylline, ephedrine hydrochloride, and phenobarbital in a suspension formulation based on the sample-internal standard peak height ratio.
Specificity of spectrophotometric determination of ephedrine and other phenalkanolamine drugs as benzaldehydes after periodate oxidation.
- Chemistry, BiologyJournal of pharmaceutical sciences
- 1971
The procedure affords very high selectivity for phenalkanolamine drugs together with greater sensitivity and facility than are provided by most extant methods for this important group of compounds.
THE UNITED STATES PHARMACOPEIA.
- Medicine
- 1908
The Pharmacopeia was called into being by physicians in 1820, and in 1850 pharmacists were admitted to the convention; since then physicians have gradually relinquished control to pharmacists, and to-day the authors are confronted with an anomalous condition.