High-pressure gas phase femtosecond laser ionization mass spectrometry.

  title={High-pressure gas phase femtosecond laser ionization mass spectrometry.},
  author={Jiahui Peng and Noah Puskas and P. B. Corkum and David Michael Rayner and Alexandre V. Loboda},
  journal={Analytical chemistry},
  volume={84 13},
We describe a novel ion source for analytical mass spectrometry based on femtosecond laser ionization at pressures at and above atmospheric and characterize its performance when coupled to a tandem quadrupole/time-of-flight mass spectrometer. We assess source saturation limits, ionization and sampling efficiencies, the effective ionization volume, and limits of detection. We demonstrate 100% efficient ionization for a set of organic compounds and show that the degree of ion fragmentation over a… 

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