High-precision structural analysis of subnuclear complexes in fixed and live cells via spatially modulated illumination (SMI) microscopy

@article{Reymann2008HighprecisionSA,
  title={High-precision structural analysis of subnuclear complexes in fixed and live cells via spatially modulated illumination (SMI) microscopy},
  author={J. Reymann and D. Baddeley and M. Gunkel and P. Lemmer and Werner Stadter and Thibaud Jegou and K. Rippe and C. Cremer and U. Birk},
  journal={Chromosome Research},
  year={2008},
  volume={16},
  pages={367-382}
}
Spatially modulated illumination (SMI) microscopy is a method of wide field fluorescence microscopy featuring interferometric illumination, which delivers structural information about nanoscale architecture in fluorescently labelled cells. The first prototype of the SMI microscope proved its applicability to a wide range of biological questions. For the SMI live cell imaging this system was enhanced in terms of the development of a completely new upright configuration. This so called Vertico… Expand
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