High plasma concentrations of autoantibodies against native peptide 210 of apoB-100 are related to less coronary atherosclerosis and lower risk of myocardial infarction.

@article{Sjgren2008HighPC,
  title={High plasma concentrations of autoantibodies against native peptide 210 of apoB-100 are related to less coronary atherosclerosis and lower risk of myocardial infarction.},
  author={Per Sj{\"o}gren and Gunilla Nordin Fredrikson and Ann Samneg{\aa}rd and Carl-G{\"o}ran Ericsson and John Ohrvik and Rachel M. Fisher and Jan Nilsson and Anders Hamsten},
  journal={European heart journal},
  year={2008},
  volume={29 18},
  pages={2218-26}
}
AIMS We examined whether antibodies against peptides 45 and 210 of apoB-100 are related to myocardial infarction (MI) and severity of coronary atherosclerosis. METHODS AND RESULTS Three hundred and eighty-seven survivors of a first MI (aged <60 years) and 387 sex- and age-matched controls were characterized in detail. IgG and IgM autoantibodies against native and malondialdehyde (MDA)-modified peptides 45 and 210 of apoB-100 (amino acids 661-680 and 3136-3155) were quantified in plasma and… CONTINUE READING

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