High physiological levels of melatonin in the bile of mammals.

@article{Tan1999HighPL,
  title={High physiological levels of melatonin in the bile of mammals.},
  author={Dunxian Tan and L. Manchester and Russell J Reiter and Wen-bo Qi and Martha A. Hanes and Nancy Farley},
  journal={Life sciences},
  year={1999},
  volume={65 23},
  pages={2523-9}
}
Bile is an important physiological bodily fluid which functions in the regulation of cholesterol metabolism, promotes the absorption of lipid and fat-soluble vitamins by the gut and serves in the excretion of toxic substances from the liver. Conversely, due to autooxidative processes bile is highly toxic to the hepatocyte and gastrointestinal epithelium. In this investigation, extremely high day time physiological levels of the endogenous antioxidant, melatonin, were measured in the bile of… CONTINUE READING

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