High phosphorylation of HBV core protein by two alpha-type CK2-activated cAMP-dependent protein kinases in vitro.

Abstract

Two alpha-type CK2-activated PKAs (CK2-aPKAIalpha and CK2-aPKAIIalpha) were biochemically characterized in vitro using GST-HBV core fusion protein (GST-Hcore) and GST-Hcore157B as phosphate acceptors. It was found that (i), in the absence of cAMP, these two CK2-aPKAs phosphorylated both Ser-170 and Ser-178 on GST-Hcore and Hcore157B; (ii) this… (More)

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@article{Enomoto2006HighPO, title={High phosphorylation of HBV core protein by two alpha-type CK2-activated cAMP-dependent protein kinases in vitro.}, author={Masato Enomoto and Yoshitaka Sawano and Seiji Kosuge and Yuko Yamano and Kazuyuki Kuroki and Kenzo Ohtsuki}, journal={FEBS letters}, year={2006}, volume={580 3}, pages={894-9} }