High-performance thin-layer chromatography based concurrent estimation of biomarkers ent-phyllanthidine and rutin in the dried aerial parts of Flueggea virosa

  title={High-performance thin-layer chromatography based concurrent estimation of biomarkers ent-phyllanthidine and rutin in the dried aerial parts of Flueggea virosa},
  author={Nasir Ali Siddiqui and Ramzi A. Mothana and Adnan Jathlan Al-Rehaily and Perwez Alam and Muhammad N. Yousaf and Sarfaraz Ahmed and Abdulrahman A Alatar},
  journal={Saudi Pharmaceutical Journal : SPJ},
  pages={696 - 702}
6 Citations

Figures and Tables from this paper

High-performance thin-layer chromatographic investigation of rutin in the leaves of Phoenix sylvestris in sequence with pharmacognostical and phytochemical evaluation
The current research aimed to investigate the pharmacognostical, phytochemical and quantification of rutin in leaves of Phoenix sylvestris by high-performance thin-layer chromatographic (HPTLC)
High-Performance Thin-Layer Chromatography (HPTLC) for Analysis of Herbal Drugs
  • P. Mukherjee
  • Biology
    Quality Control and Evaluation of Herbal Drugs
  • 2019
High Performance Thin Layer Chromatography Fingerprinting Studies of Croton klotzschianus (Wight) Thw.
Most of the traditional medicinal plants in India are not scientifically validated. Scientific evaluation along with traditional knowledge is essential to obtain effective drugs for commercial
The anticancer potential of the dietary polyphenol rutin: Current status, challenges, and perspectives
Rutin is a promising natural dietary compound with promising anticancer potential and can be widely used in functional foods, dietary supplements, and pharmaceuticals for the prevention and management of cancer.
A novel design to screen chlorogenic acid-producing microbial strains from the environment
A plate-screening method based on the specific color development of complexes formed between chlorogenic acid, a valuable plant-derived compound, and aluminum (III), to detect chlorogenic Acid-producing microbial strains, providing a highly efficient and low-cost tool for quick detection and subsequent identification of several newly isolated strains with chlorogenicacid-producing potential.


Simultaneous quantification of biomarkers bergenin and menisdaurin in the methanol extract of aerial parts of Flueggea virosa by validated HPTLC densitometric method.
The developed HPTLC method permitted the simultaneous quantification of bergenin and menisdaurin and showed good resolution and resolution from other constituents of extract; hence, the method can be used to standardize herbal formulations as well as bulk drugs for bergen in and menischaurin.
Quantitative analysis of biomarker rutin in different species of genus Ficus by validated NP and RP-HPTLC methods.
Biomarker rutin was analyzed in methanol extracts of leaves of five different species of genus Ficus by NP-HPTLC and RP- HPTLC methods and was found to be more accurate, precise and sensitive than Method I.
Phytochemical screening, acute toxicity and analgesic properties of aqueous extract of flueggea virosa's root in rats
The aqueous extract of the Flueggea virosa's root produces modest yield of extract and possesses potent phytochemicals, some measure of acute safety and significant analgesic properties.
A review on plant-based rutin extraction methods and its pharmacological activities.
  • L. S. Chua
  • Chemistry
    Journal of ethnopharmacology
  • 2013
Leishmanicidal Activity of (+)-Phyllanthidine and the Phytochemical Profile of Margaritaria nobilis (Phyllanthaceae)
The low toxicity to macrophages and the effects against promastigote and amastigotes are suggestive that (+)-phyllanthidine could be a promising antileishmanial agent for treating cutaneous leishmaniasis.
Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid
This work reviewed characteristic, pharmacokinetic, and metabolic effects of rutin in all experimental and human studies and found this flavonoid appears to be a potent component that could be considered in the treatment of several gastrointestinal diseases and diabetes.
Chemical Constituents from Flueggea virosa
Antioxidant flavonoid glycosides from the leaves of Ficus pumila L.
Behavioural effects of the methanolic root bark extract of Securinega virosa in rodents.
The results suggest that methanolic root bark extract of S. virosa contains biologically active principles that are sedative in nature and lend pharmacological credence to the ethnomedical use of the plant.