High-performance metabolic profiling with dual chromatography-Fourier-transform mass spectrometry (DC-FTMS) for study of the exposome

@article{Soltow2011HighperformanceMP,
  title={High-performance metabolic profiling with dual chromatography-Fourier-transform mass spectrometry (DC-FTMS) for study of the exposome},
  author={Quinlyn A. Soltow and Frederick H. Strobel and Keith G Mansfield and Lynn M. Wachtman and Youngja Park and D. H. P. Jones},
  journal={Metabolomics},
  year={2011},
  volume={9},
  pages={132-143}
}
Studies of gene–environment (G × E) interactions require effective characterization of all environmental exposures from conception to death, termed the exposome. The exposome includes environmental exposures that impact health. Improved metabolic profiling methods are needed to characterize these exposures for use in personalized medicine. In the present study, we compared the analytic capability of dual chromatography-Fourier-transform mass spectrometry (DC-FTMS) to previously used liquid… CONTINUE READING