High-performance liquid chromatography and micellar electrokinetic chromatography of taxol and related taxanes from bark and needle extracts of Taxus species.

Abstract

High-performance liquid chromatography (HPLC) and micellar electrokinetic chromatography (MEKC) were applied for the separation of taxol, cephalomannine, and baccatin III in crude extracts from the needle and bark of Taxus species. The chromatogram of the bark extract was cleaner than that of the needle allowing a more reliable detection of taxol and… (More)

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@article{Chan1994HighperformanceLC, title={High-performance liquid chromatography and micellar electrokinetic chromatography of taxol and related taxanes from bark and needle extracts of Taxus species.}, author={K. C. Chan and A. Alvarado and M T Mcguire and Gary M. Muschik and Haleem J. Issaq and Kenneth M Snader}, journal={Journal of chromatography. B, Biomedical applications}, year={1994}, volume={657 2}, pages={301-6} }