High performance liquid chromatography analysis of D-penicillamine by derivatization with N-(1-pyrenyl)maleimide (NPM).

@article{Yusof2000HighPL,
  title={High performance liquid chromatography analysis of D-penicillamine by derivatization with N-(1-pyrenyl)maleimide (NPM).},
  author={Mazina Yusof and R. T. Neal and Nuray M. Aykin and Nuran Ercal},
  journal={Biomedical chromatography : BMC},
  year={2000},
  volume={14 8},
  pages={535-40}
}
D-Penicillamine (2-amino-3-mercapto-3-methylbutanoic acid), a well-known heavy metal chelator, is the drug of choice in the treatment of Wilson's disease and is also effective for the treatment of several disorders including rheumatoid arthritis, primary biliary cirrhosis, scleroderma, fibrotic lung diseases and progressive systemic sclerosis. The method… CONTINUE READING