High-performance liquid chromatographic determination of protoporphyrin and zinc protoporphyrin in blood.

@article{Smith1980HighperformanceLC,
  title={High-performance liquid chromatographic determination of protoporphyrin and zinc protoporphyrin in blood.},
  author={Roger M. Smith and Dominic Doran and M S Mazur and Brian Bush},
  journal={Journal of chromatography},
  year={1980},
  volume={181 3-4},
  pages={319-27}
}
Zinc protoporphyrin and protoporphyrin free acid in blood were determined by high-performance liquid chromatography on a C18 column. Results for 63 human blood samples obtained through a lead poisoning detection program compared favorably with the widely-used ethyl acetate--acetic acid extraction determination. Blood from 16 rats which had been maintained on water heavily spiked with chloroform or bromodichloromethane and blood from a lead-poisoned cow were examined by this procedure. 

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