High-performance liquid chromatographic method optimization for ondansetron assay in extemporaneous topical gel and in marketed products.

Abstract

The compounding and evaluation of ondansetron hydrochloride dihydrate topical gel, 2.5% w/w, were conducted in this study. The gelling agent was Carbopol 940. Ethanol 70% in purified water was used to dissolve the drug and disperse the gelling agent. A gel was formed by adding drops of 0.1 N sodium hydroxide solution. To assay this gel, we developed a… (More)

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Cite this paper

@article{Quamrun2014HighperformanceLC, title={High-performance liquid chromatographic method optimization for ondansetron assay in extemporaneous topical gel and in marketed products.}, author={Masuda Quamrun and Rashid Mamoon and Shams Nasheed and Mullins Randy}, journal={International journal of pharmaceutical compounding}, year={2014}, volume={18 6}, pages={520-5} }