High-performance affinity chromatography: a powerful tool for studying serum protein binding.

@article{Hage2002HighperformanceAC,
  title={High-performance affinity chromatography: a powerful tool for studying serum protein binding.},
  author={David S Hage},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2002},
  volume={768 1},
  pages={3-30}
}
  • David S Hage
  • Published 2002 in
    Journal of chromatography. B, Analytical…
High-performance affinity chromatography (HPAC) is a method in which a biologically-related ligand is used as a stationary phase in an HPLC system. This approach is a powerful means for selectively isolating or quantitating agents in complex samples, but it can also be employed to study the interactions of biological systems. In recent years there have been numerous reports in which HPAC has been used to examine the interactions of drugs, hormones and other substances with serum proteins. This… CONTINUE READING

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