High number of tumour-infiltrating lymphocytes is associated with apoptosis in non-small cell lung carcinoma.

@article{TrmnenNpnkangas2001HighNO,
  title={High number of tumour-infiltrating lymphocytes is associated with apoptosis in non-small cell lung carcinoma.},
  author={U T{\"o}rm{\"a}nen-N{\"a}p{\"a}nkangas and Ylermi M Soini and Paavo K P{\"a}{\"a}kk{\"o}},
  journal={APMIS : acta pathologica, microbiologica, et immunologica Scandinavica},
  year={2001},
  volume={109 7-8},
  pages={
          525-32
        }
}
AIM To test whether the number of tumour-infiltrating mononuclear cells (MNC), namely T-lymphocytes (TIL) and, to a lesser degree, B-lymphocytes and macrophages, is associated with tumour cell apoptosis in non-small cell lung carcinoma (NSCLC). METHODS AND RESULTS Eighty-four non-small cell lung tumours were analysed with specific antibodies and the extent of apoptosis was determined using 3'-end labelling of fragmented DNA (TUNEL). All parameters were determined from the same tumour areas… CONTINUE READING
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