High mutation rates in the mitochondrial genomes of Daphnia pulex.

@article{Xu2012HighMR,
  title={High mutation rates in the mitochondrial genomes of Daphnia pulex.},
  author={Sen Xu and Sarah Schaack and Amanda L Seyfert and Eunjin Choi and Michael Lynch and Melania E. A. Cristescu},
  journal={Molecular biology and evolution},
  year={2012},
  volume={29 2},
  pages={763-9}
}
Despite the great utility of mitochondrial DNA (mtDNA) sequence data in population genetics and phylogenetics, key parameters describing the process of mitochondrial mutation (e.g., the rate and spectrum of mutational change) are based on few direct estimates. Furthermore, the variation in the mtDNA mutation process within species or between lineages with contrasting reproductive strategies remains poorly understood. In this study, we directly estimate the mtDNA mutation rate and spectrum using… CONTINUE READING