High mutation rates have driven extensive structural polymorphism among human Y chromosomes

@article{Repping2006HighMR,
  title={High mutation rates have driven extensive structural polymorphism among human Y chromosomes},
  author={Sjoerd Repping and Saskia K M van Daalen and Laura G. Brown and Cindy M. Korver and Julian Lange and Janet D. Marszalek and Tatyana Pyntikova and Fulco van der Veen and Helen Skaletsky and David C. Page and Steve Rozen},
  journal={Nature Genetics},
  year={2006},
  volume={38},
  pages={463-467}
}
Although much structural polymorphism in the human genome has been catalogued, the kinetics of underlying change remain largely unexplored. Because human Y chromosomes are clonally inherited, it has been possible to capture their detailed relationships in a robust, worldwide genealogical tree. Examination of structural variation across this tree opens avenues for investigating rates of underlying mutations. We selected one Y chromosome from each of 47 branches of this tree and searched for… 
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