High mutation rate of a long microsatellite allele in Drosophila melanogaster provides evidence for allele-specific mutation rates.

@article{Schltterer1998HighMR,
  title={High mutation rate of a long microsatellite allele in Drosophila melanogaster provides evidence for allele-specific mutation rates.},
  author={Christian Schl{\"o}tterer and Robert Ritter and Bettina Harr and Gottfried Brem},
  journal={Molecular biology and evolution},
  year={1998},
  volume={15 10},
  pages={1269-74}
}
Within recent years, microsatellite have become one of the most powerful genetic markers in biology. For several mammalian species, microsatellite mutation rates have been estimated on the order of 10(-3)-10(-5). A recent study, however, demonstrated mutation rates in Drosophila melanogaster of at least one order of magnitude lower than those in mammals. To further test this result, we examined mutation rates of different microsatellite loci using a larger sample size. We screened 24… CONTINUE READING

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