High-molecular weight protein toxins of marine invertebrates and their elaborate modes of action.

@article{Butzke2010HighmolecularWP,
  title={High-molecular weight protein toxins of marine invertebrates and their elaborate modes of action.},
  author={Daniel Butzke and Andreas Luch},
  journal={EXS},
  year={2010},
  volume={100},
  pages={213-32}
}
High-molecular weight protein toxins significantly contribute to envenomations by certain marine invertebrates, e.g., jellyfish and fire corals. Toxic proteins frequently evolved from enzymes meant to be employed primarily for digestive purposes. The cellular intermediates produced by such enzymatic activity, e.g., reactive oxygen species or lysophospholipids, rapidly and effectively mediate cell death by disrupting cellular integrity. Membrane integrity may also be disrupted by pore-forming… CONTINUE READING
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