High metabolic activity in the dorsal vagal complex of Brattleboro rats

@article{Shaver1989HighMA,
  title={High metabolic activity in the dorsal vagal complex of Brattleboro rats},
  author={S. W. Shaver and M. Kadekaro and P. Gross},
  journal={Brain Research},
  year={1989},
  volume={505},
  pages={316-320}
}
Receptor densities for angiotensin II and atriopeptin are particularly high in the dorsal vagal complex (DVC) of the caudal medulla oblongata. Measurements of glucose metabolism in individual components of the DVC, compared with those in Long-Evans rats, revealed that the area postrema was activated selectively both in water-sated and water-deprived Brattleboro rats, which have high circulating levels of angiotensin II. Other parts of the DVC, including subnuclei of the nucleus of the solitary… Expand
3 Citations
Efferent metabolic effects of area postrema stimulation in renal hypertensive rats
TLDR
Disturbances of brainstem neurotransmission or tissue reactivity to postremal pathway activation thus appear to be part of the central pathophysiology of chronic renal hypertension. Expand
Atriopeptin prevents angiotensin II-stimulated glucose utilization in the subfornical organ
TLDR
Findings indicate that atriopeptin III, an atrial natriuretic peptide, may act at the level of subfornical organ to antagonize the dipsogenic action of ANG II. Expand

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